If a parent in the proband is understood to have the pathogenic variant identified while in the proband, the danger into the sibs of inheriting the pathogenic variant is fifty%. As a result of reduced penetrance, sibs who inherit the pathogenic variant might or might not establish aHUS (see Penetrance). https://lukasecvme.techionblog.com/31961615/the-ultimate-guide-to-ahu-s